抗病毒药物代谢物及杂质标准品不再难找!
抗病毒药物药代动力学研究是设计创新抗病毒药物的源泉。福沙那伟钙是安泼那韦的前药(prodrug)。代谢使获得安泼那韦时间延长，福沙那伟钙缓慢释放安泼那韦并减少所需药丸数。2004年12月制造商停止生产安泼那韦；用前药福沙那伟钙。又如泛昔洛韦是喷昔洛韦的前药，口服生物利用度从1.5%改善至75~77%。缬更昔洛韦是更昔洛韦的前药。前药与活性代谢物有不同血药浓度曲线有各自的用途。
金畔生物针对抗病毒药物动力学研究提供抗病毒药物代谢物及杂质标准品。
产品信息：
|
货号 |
品名 |
CAS No. |
分子式 |
包装规格 |
应用 |
|
T350050 |
2-Thio-2’-deoxy Cytidine |
169557-13-5 |
C9H13N3O3S |
10/100mg |
2-含硫吡啶核苷 |
|
D230625 |
Delavirdine |
136817-59-9 |
C22H28N6O3S |
10/100mg |
BHAP逆转录酶抑制剂 |
|
D230630 |
Delavirdine Mesylate |
147221-93-0 |
C23H32N6O6S2 |
10/100mg |
BHAP逆转录酶抑制剂 |
|
D528800 |
Dolutegravir |
1051375-16-6 |
C20H19F2N3O5 |
2.5/25mg |
Dolutegravir分析标准品 |
|
I525000 |
Indinavir Sulfate |
157810-81-6 |
C36H49N5O8S |
5/50mg |
Hiv -1蛋白酶抑制剂 |
|
I525001 |
Indinavir |
150378-17-9 |
C36H49N5O8S |
10/100mg |
Hiv – 1蛋白酶抑制剂 |
|
N391275 |
Nevirapine |
129618-40-2 |
C15H14N4O |
5/50/250mg |
hiv – 1强有力的(IC50 = 84 nm)和选择性非核苷逆转录酶抑制剂 |
|
N389750 |
Nelfinavir Mesylate |
159989-65-8 |
C33H49N3O7S2 |
10/100mg |
HIV蛋白酶抑制剂 |
|
C633150 |
Cobicistat |
1004316-88-4 |
C40H53N7O5S2 |
10/25/50mg |
HIV蛋白酶抑制剂 |
|
P681025 |
Podorhizol β-D-Glucopyranoside |
17187-73-4 |
C28H34O13 |
2.5/25mg |
Podorhizol β-D-吡喃葡萄糖苷，抗病毒剂 |
|
A607897 |
(2S,3S,5S)-5-Amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride-d6 |
|
C37H43D6ClN6O5S2 |
0.5/5mg |
Ritonavor前体 |
|
D201750 |
3-Deazaneplanocin A |
120964-45-6 |
C12H15ClN4O3 |
1/5/10mg |
S-adenosylhomocysteineydrolase水解酶抑制剂 |
|
C982175 |
3-Cyano-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazole |
40371-99-1 |
C14H16N4O7 |
25/250mg |
Viramidine 衍生物 |
|
A105015 |
ent-Abacavir |
136470-79-6 |
C14H18N6O |
5/50mg |
阿巴卡韦对映体，核苷逆转录酶抑制剂 |
|
A192450 |
Acyclovir N-Methylene Dimer |
|
C17H22N10O6 |
1/10mg |
阿昔洛韦二聚杂质 |
|
F696850 |
4-Formyl Antipyrine |
950-81-2 |
C12H12N2O2 |
2.5/25g |
安替比林衍生物 |
|
O239020 |
Octaverine Hydrochloride |
6775-26-4 |
C23H28ClNO5 |
10/100mg |
奥他维林盐酸盐分析标准品 |
|
T662400 |
3’’-O-Tosyl Entecavir |
|
C19H21N5O5S |
5/50mg |
保护的恩替卡韦 |
|
N389752 |
Nelfinavir-d3 |
|
C32H42D3N3O4S |
1/10mg |
标记的HIV蛋白酶抑制剂 |
|
L379002 |
Levovirin -13C5 |
|
C313C5H12N4O5 |
0.5/5mg |
标记的Levovirin类似物 |
|
A634402 |
Amprenavir-d4 |
|
C25H31D4N3O6S |
1/10mg |
标记的安普那韦 |
|
F696852 |
4-Formyl Antipyrine-d3 |
|
C12H9D3N2O2 |
5/50mg |
标记的安替比林衍生物 |
|
G235022 |
Ganciclovir Mono-O-propionate-d5 |
|
C12H12D5N5O5 |
1/10mg |
标记的更昔洛韦Mono-O-丙酸酯类似物。是更昔洛韦潜在的前体。抗病毒剂。 |
|
M526802 |
2’-Monodehydroxy-2’-chloro Ganciclovir-d5 |
|
C9H7D5ClN5O3 |
1/10mg |
标记的更昔洛韦杂质 |
|
B190250 |
Benzethonium Chloride |
121-54-0 |
C27H42ClNO2 |
10/100g |
标记的合成的季铵盐具有表面活性剂、杀菌和抗感染的特性 |
|
B190252 |
Benzethonium-d7 Chloride |
|
C27H35D7ClNO2 |
5/50mg |
标记的合成的季铵盐具有表面活性剂、杀菌和抗感染的特性 |
|
L172502 |
Lamivudine-15N2,13C |
|
C713CH11N15N2O3S |
1/10mg |
标记的拉米夫定 |
|
E588527 |
5’-Epi Lamivudine-15N2,13C |
|
C713CH11N15N2O3S |
0.5/5mg |
标记的拉米夫定差向异构体 |
|
R414477 |
Ribavirin-13C5 |
|
C313C5H12N4O5 |
1/10mg |
标记的利巴韦林 |
|
D297432 |
Desthiazolylmethyloxycarbonyl Ritonavir-d6 |
|
C32H39D6N5O3S |
1/10mg |
标记的利托那韦代谢物 |
|
R701692 |
(5R)-Rupintrivir-d3 |
|
C31H36D3FN4O7 |
0.25/2.5mg |
标记的芦平曲韦5R-enantiomer |
|
N391277 |
Nevirapine-d5 See N391278 |
|
C15H9D5N4O |
1/10mg |
标记的奈韦拉平 |
|
Nevirapine-d3 |
1051419-24-9 |
C15H11D3N4O |
2.5/25mg |
标记的奈韦拉平 |
|
|
H948627 |
2-Hydroxy Nevirapine-d3 |
|
C15H11D3N4O2 |
1/10mg |
标记的奈韦拉平代谢物 |
|
H948632 |
3-Hydroxy Nevirapine-d3 |
|
C15H11D3N4O2 |
0.5/5mg |
标记的奈韦拉平代谢物 |
|
P580352 |
Pleconaril-d8 (Major) |
1346602-36-5 |
C18H10D8F3N3O3 |
1/10mg |
标记的普拉康纳利，小核糖核酸病毒复制抑制剂，抗病毒。 |
|
S135002 |
Saquinavir-d9 |
1356355-11-7 |
C38H41D9N6O5 |
1/10mg |
标记的沙奎那韦 |
|
S135003 |
Saquinavir-d6 |
|
C38H44D6N6O5 |
10mg |
标记的沙奎那韦 |
|
E425002 |
rac Efavirenz-d4 Also see: E425003 |
|
C14H5D4ClF3NO2 |
1/10mg |
标记的依法韦仑 |
|
E425003 |
rac Efavirenz-d5 (major) |
|
C14H4D5ClF3NO2 |
0.5/5mg |
标记的依法韦仑 |
|
D232945 |
2’-Deoxy-2’-fluoro Cytidine |
10212-20-1 |
C9H12FN3O4 |
100mg/1g |
丙型肝炎次基因组强有力抑制剂 |
|
E558900 |
Entecavir |
142217-69-4 |
C12H15N5O3 |
10/100mg |
恩替卡韦 |
|
9-((1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-2-(2-oxo-2-phenylethyl)-1H-purin-6(9H)-one |
|
C19H19N5O4 |
5mg |
恩替卡韦苯甲酰保护衍生物，抗病毒 |
|
|
E558920 |
1’-epi-Entecavir |
|
C12H15N5O3 |
10/25mg |
恩替卡韦差向异构体杂质 |
|
E558925 |
3’-epi-Entecavir |
|
C12H15N5O3 |
10/25mg |
恩替卡韦差向异构体杂质 |
|
E558930 |
4’-epi-Entecavir |
1367369-80-9 |
C12H15N5O3 |
2.5/25mg |
恩替卡韦差向异构体杂质 |
|
H946560 |
9-((1S,3R,4S)-4-Hydroxy-3-(((4-methoxyphenyl)diphenylmethoxy)methyl)-2-methylenecyclopentyl)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-1H-purin-6(9H)-one |
|
C52H47N5O5 |
10/100mg |
恩替卡韦差向异构体杂质 |
|
H946565 |
9-((1S,3R,4R)-4-Hydroxy-3-(((4-methoxyphenyl)diphenylmethoxy)methyl)-2-methylenecyclopentyl)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-1H-purin-6(9H)-one |
|
C52H47N5O5 |
2.5/25mg |
恩替卡韦差向异构体杂质 |
|
M266070 |
(1S,2R,4S)-2-(((4-Methoxyphenyl)diphenylmethoxy)methyl)-4-(2-(((4-methoxyphenyl)diphenylmethyl)amino)-6-oxo-1H-purin-9(6H)-yl)-3-methylenecyclopentyl 4-nitrobenzoate |
|
C59H50N6O8 |
5/50mg |
恩替卡韦差向异构体杂质 |
|
E558905 |
ent-Entecavir |
188399-46-4 |
C12H15N5O3 |
1/10mg |
恩替卡韦对映体杂质 |
|
D417552 |
3’,5’-Di-O-benzyl Entecavir-13C2,15N |
|
C2413C2H27N415NO3 |
0.5/5mg |
恩替卡韦对映体中间体 |
|
M263075 |
(1R,2R,3R,5R)-5-[(4-Methoxyphenyl)-diphenylmethylamino-6-bezyloxy-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol |
|
C52H49N5O5 |
2.5/25mg |
恩替卡韦对映体中间体 |
|
M263080 |
2-N-[(4-Methoxyphenyl)-diphenylmethyl]-4,6’-O-dibenzyl ent-Entecavir |
1354695-79-6 |
C53H49N5O4 |
1/10mg |
恩替卡韦对映体中间体 |
|
D417550 |
3’,5’-Di-O-benzyl Entecavir |
142217-81-0 |
C26H27N5O3 |
25/250mg |
恩替卡韦对映体中间体 |
|
E558935 |
(1R,3R,4R)-Entecavir |
1367369-76-3 |
C12H15N5O3 |
10/25/50mg |
恩替卡韦同分异构体杂质 |
|
H939670 |
8-Hydroxy Entecavir |
|
C12H15N5O4 |
10/25mg |
恩替卡韦杂质 |
|
D417150 |
3’,5’-Di-O-benzoyl Fialuridine (1:3 α/β Mixture)(see D417160) |
|
C23H18FIN2O7 |
25/250mg |
非阿尿苷中间体 |
|
D417160 |
3’,5’-Di-O-benzoyl Fialuridine |
97614-45-4 |
C23H18FIN2O7 |
25/250mg |
非阿尿苷中间体 |
|
C365545 |
6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline |
391860-73-4 |
C13H9ClF3N |
500mg/5g |
非核苷hiv – 1逆转录酶抑制剂。 |
|
E425000 |
Efavirenz |
154598-52-4 |
C14H9ClF3NO2 |
10/100mg |
非核苷hiv – 1逆转录酶抑制剂。 |
|
G235020 |
Ganciclovir Mono-O-propionate |
194159-18-7 |
C12H17N5O5 |
50/500mg |
更昔洛韦Mono-O-丙酸酯类似物。是更昔洛韦潜在的前体。抗病毒剂。 |
|
G235030 |
Ganciclovir Triphosphate |
86761-38-8 |
C9H16N5O13P3 |
1/10mg |
更昔洛韦三磷酸盐 |
|
M526800 |
2’-Monodehydroxy-2’-chloro Ganciclovir |
108436-36-8 |
C9H12ClN5O3 |
50/500mg |
更昔洛韦杂质 |
|
C379785 |
9-[[2-chloroprop-2-en-1-yl)oxy]methyl]guanine |
|
C9H10ClN5O2 |
25/50/100mg |
更昔洛韦杂质 |
|
F335002 |
Fialuridine-15N2,13C |
|
C813CH10FI15N2O5 |
10/25mg |
核苷类似物 |
|
N389765 |
Nelfinavir Sulfone |
1041389-29-0 |
C32H45N3O6S |
10/100mg |
甲磺酸奈非那韦杂质 |
|
N389770 |
Nelfinavir Sulfoxide |
1041389-28-9 |
C32H45N3O5S |
10/100mg |
甲磺酸奈非那韦杂质 |
|
P838335 |
2-Propyltriphenylphosphonium Bromide |
1530-33-2 |
C21H22BrP |
100mg/1g |
具有抗病毒活性 |
|
P681000 |
Podophyllotoxin |
518-28-5 |
C22H22O8 |
500mg/5g |
抗HPVs剂 |
|
R414475 |
Ribavirin |
36791-04-5 |
C8H12N4O5 |
100mg/250mg/1g |
抗病毒剂 |
|
E425010 |
Efavirenz Pen-3-ene-1-yne(cis/trans Mixture) |
|
C14H9ClF3NO2 |
2.5/25mg |
抗病毒剂 |
|
E555600 |
Enfuvirtide Acetate |
914454-00-5 |
C206H305N51O66 |
100mg |
抗逆转录病毒药物用于治疗艾滋病毒感染 |
|
E588525 |
5’-Epi Lamivudine |
139757-68-9 |
C8H11N3O3S |
1/10mg |
拉米夫定差向异构体标准品 |
|
L172510 |
Lamivudine Triphosphate Ammonium Salt |
1187058-42-9 |
C8H23N6O12P3S |
1/10mg |
拉米夫定代谢物 |
|
L172515 |
Lamivudine Diphosphate Ammonium Salt |
1187058-41-8 |
C8H19N5O9P2S |
10mg |
拉米夫定代谢物 |
|
L172520 |
Lamivudine Monophosphate Ammonium Salt |
1187058-40-7 |
C8H15N4O6PS |
1/10mg |
拉米夫定代谢物 |
|
L172500 |
Lamivudine |
134678-17-4 |
C8H11N3O3S |
25mg/250mg/1g |
拉米夫定分析标准品 |
|
V673002 |
Viramidine-13C5 Hydrochloride |
|