lumiprobe荧光染料Cyanine5.5 hydrazide

发表于2023年3月3日由上海金畔生物科技有限公司

lumiprobe荧光染料官网代理商水溶性荧光染料代理商脂溶性荧光染料代理商 Cyanine5.5 hydrazide

Cyanine5.5 Hydrazides Microscopy

Bulk inquiry Cyanine5.5 hydrazide

Cat. #	Quantity	Price
17070	1 mg	$110.00
27070	5 mg	$210.00
47070	25 mg	$410.00
57070	50 mg	$695.00
67070	100 mg	$1190.00

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Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.

Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.