荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP] 货号13606-AAT Bioquest荧光染料

上海金畔生物科技有限公司代理AAT Bioquest荧光染料全线产品,欢迎访问AAT Bioquest荧光染料官网了解更多信息。

荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]

荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]

荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]    货号13606 货号 13606 存储条件 在零下15度以下保存, 避免光照
规格 100 nmol 价格 6432
Ex (nm) 552 Em (nm) 578
分子量 1309.30 溶剂 DMSO
产品详细介绍

简要概述

产品基本信息

货号:13606

产品名称:荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]

规格:100 nmol

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:1309.30

溶剂:DMSO

激发波长(nm):544

发射波长(nm):575

 

产品介绍

荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]是美国AAT Bioquest生产的荧光底物,荧光标记的ADP分子用于筛选ADP结合酶和其他蛋白质靶标用于药物发现。 该ADP-TAMRA已经测试了K(d)值为0.60±0.05?M的结合犬尿氨酸单加氧酶(KMO)和来自烟曲霉和耻垢分枝杆菌的NMO,K(d)值为2.1±0.2和4.0± 分别为0.2 M(Anal Biochem。2012,425,80-7)。 在与KMO和NMO的底物和产物的竞争性结合实验中测试该测定。 NMO对于真菌和细菌的发病机制至关重要。 NMO在含异羟肟酸的铁载体的生物合成中催化正弦和鸟氨酸的羟基化。 抑制KMO,催化犬尿氨酸转化为3-羟基犬尿氨酸,缓解神经退行性疾病,如亨廷顿氏症和阿尔茨海默氏症以及寄生虫布氏锥虫引起的脑部感染。金畔生物是AAT Bioquest的中国代理商,为您提供最优质的荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]。 

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参考文献

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Ca2+ binding to sarcoplasmic reticulum ATPase phosphorylated by Pi reveals four thapsigargin-sensitive Ca2+ sites in the presence of ADP
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Evidence for proximal cysteine and lysine residues at or near the active site of arginine kinase of Stichopus japonicus
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Conformational dynamics of DnaB helicase upon DNA and nucleotide binding: analysis by intrinsic tryptophan fluorescence quenching
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Journal: Biochemistry (2003): 1910

D1 ring is stable and nucleotide-independent, whereas D2 ring undergoes major conformational changes during the ATPase cycle of p97-VCP
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Journal: J Biol Chem (2003): 32784

说明书
荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP].pdf